Scientists have perfected mini cultured 3-D structures that grow and function much like the outer mantle -- the key working tissue, or cortex -- of the brain of the person from whom they were derived. Strikingly, these 'organoids' buzz with neuronal network activity. Cells talk with each other in circuits, much as they do in our brains.
Immunotherapy with the anti-PD-1 antibody pembrolizumab decreased the size of tumors by 30 percent or more in 24.8 percent of 132 patients with recurrent or metastatic head and neck cancer. That's nearly twice as effective as the current preferred treatment.
In Science Advances, University at Buffalo researchers will report that they have managed to turn E. coli into tiny factories for producing new forms of the popular antibiotic erythromycin -- including three that were shown in the lab to kill drug-resistant bacteria.
As drought continues, and demand grows, researchers are looking to new models to improve the Rio Grande region's drought resiliency.
If you are over age 75, and taking an anticoagulant, the old standard may be the gold standard, Mayo Clinic researchers and collaborators have determined.
While the overall rate of colorectal cancer (CRC) is declining, CRC specifically among young patients is increasing. Previous studies have shown that CRC in patients younger than 50 years old tends to be more aggressive than CRC in older patients. A new study offers early evidence of genetic differences between CRC in young and old patients, possibly pointing toward different treatments and strategies in combating the young form of the disease.
Scientists have created a new carbon material that significantly improves the performance of batteries and supercapacitors.
As in adults, migraine surgery is effective for selected adolescent patients with severe migraine headaches that don't respond to standard treatments, reports a new study.
Scientists have been researching the process of laser pulse filamentation -- the effect produced when a laser beam propagating in air focuses into a filament. The researchers discovered how this process influences the preliminary transition of a beam passing through quartz glass, which has applications in the field of nonlinear optics.
Researchers are exploring new approaches to designing prosthetic hands capable of providing "sensory feedback." New advances have been made toward developing prostheses with a sense of touch.
A stagnant upper-air pattern that spread numerous storms and heavy rains from central Texas up into Oklahoma has resulted in record flooding for parts of the Lone Star State.
Restricting access to firearms for people who misuse alcohol could prevent firearm violence, but policies that more clearly define alcohol misuse should be developed to facilitate enforcement, according to a review of existing research and public policies.
Earth researchers have devised a technique that transforms the tiny tremors generated by the everyday hustle and bustle of city life into a tool for probing the subsurface of Earth.
R-loops, thought to initiate cellular mutations, genome breaks and diseases, may be identified with an accuracy of between 80-90 percent at lower costs and effort.
There are 10,000 components that can be used to make cosmetics. These components have to be monitored to guarantee consumer safety. Scientists have now developed three 'green' analytical methods to simultaneously analyze various components used in cosmetics. In these methods very little solvent is used and very little residue is produced in comparison with other analytical techniques.
The first clinical study of the anticancer effects of the novel agent entolimod are now available. Findings confirm preclinical evidence that the agent, which is derived from salmonella flagellin, is worthy of further investigation as treatment for some of the most common and most resilient solid-tumor cancers.
Phase III results indicate that acupuncture-like, transcutaneous electrical nerve stimulation may be equally effective as pilocarpine, the current prescription medication in a pill, to treat radiation-induced xerostomia (dry mouth), according to a new study published.
Engineers have created tiny acoustic vortices and used them to grip and spin microscopic particles suspended in water.
When people on methadone maintenance treatment (MMT) are incarcerated in the United States, they are almost always forced off of the addiction-controlling medicine. In a randomized trial, inmates allowed to stay on MMT while in jail proved much more likely to seek treatment after release than those whose treatment was interrupted.
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